I do not know of any tract of country in which, within so narrow a compass, may be found an equal variety in the influences of light and shadow upon the sublime or beautiful features of landscape.

.The south is one of the most popular areas with Windermere lake (the largest), popular towns like Kendal and Windermere, and easy access from the south. This region has less dramatic mountainous terrain, but has lots of attractions and things to do, and plenty of accommodation options. The area can be VERY busy during the summer with difficulty parking, driving, and getting around.
The south is best for a holiday mooching around towns and watersports on the lake.

The west is a bit of an undiscovered region in the lakes, and has lots of beautiful, yet desolate or isolated, scenery, and areas to explore. Most of the towns in the west are traditionally very working-class and remain under privileged with high levels of unemployment. The West is lacking in the amount of tourism the other areas get, so consequently, there is less accommodation and less things to do in the area.
The West is best for Mountain explorers, and those who seek a bit of isolation.

The north of the Lakes is a real gem with beautiful towns, like Keswick and Cockermouth to explore, and beautiful lakes like Derwent water. The north is arguably one of the best areas that balances mountains, lakes, picturesque towns, and villages with things to do and explore, without a huge amount of tourism and traffic. Although Keswick can get very busy during the summer months.
The north is good for those looking for a balance between fell walking Lakes and visiting towns and attractions, and who don’t mind travelling a bit further to get there.

Similarly to the west - the east, has many undiscovered gems such as Haweswater, but also has very popular lake destinations, for example, Ullswater and Pooley Bridge. Towns like Penrith, offer an easy and convenient stepping stone into the northern and eastern part of the Lake District, but Penrith is well worth a visit and has recently being awarded one of the best towns to live.
The east has some of the best access from the M6, A6 and A66, and is also conveniently close to the more central Lake District areas.
The east has a good mix of lakes, mountains (both high and low), flatter or less hilly beauty spots, and picturesque towns and villages with too many attractions to list.
The east is best for those who are looking for an all-round balance, and access to all the National Park has to offer, yet has great fell walks, both popular (eg Hellvellyn) and more isolated, popular lakes  (eg Ullswater) or isolated lakes (eg Haweswater), and easy access to the rest of the attractions and destinations the Lake District has to offer, as well as being easily accessible by main road.